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SHUKUROVA UMIDA
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SHUKUROVA UMIDA
2015-05-4

SHUKUROVA UMIDA

FEATURES OF CLINICAL CURRENT AND TREATMENT CHRONIC RECURRENT APHTOUS STOMATITIS AT PREGNANT WOMEN

14.00.21 - Stomatology
 
RESUME

Thesis of Umida Shukurova on the scientific degree competition of the doctor of philosophy in medicine on speciality14.00.21 – stomatology subject: “Features of clinical current and treatment chronic recurrent aphtous stomatitis at pregnant women”

Key words: chronic recurrent aphtous stomatitis (CRAS), pregnant women, pregnancy for the first time, repeated pregnancy, FarGALS, probiotics, a dysbacteriosis, nonspecific resistance of a mucous membrane of an oral cavity (MMOC).

Subjects of research: 840 women from 18 till 35 years which are being at various stages of pregnancy, and 574 not pregnant women of comparable age. 75 pregnant women with CRAS have received various kinds of pathogenetic treatment. As the control parameters of 20 pregnant women without diseases MMOC are used.

Purpose of work: To study frequency of defeat and feature of clinical current CRAS at pregnant women with development of a method of complex pathogenetic treatment.

Methods of research: Clinical, microbiological, immunological, cytological, and statistical.

The results obtained and their novelty: the integrated parameter of an estimation of weight of current CRAS (IGW). Is developed frequency affection CRAS among pregnant women is established. Pathological changes above at repeated pregnancy also are maximal in II-trimester. CRAS at pregnant women develops on a background expressed disbiotic changes of an intestines and a mouth which degree correlates with weight of clinical current. Higher direct correlation dependence of clinical displays is established with a dysbacteriosis of intestines.

The algorithm of treatment CRAS at pregnant women with inclusion of local use FarGALS with reception of probiotics under the scheme is offered.

Practical value: At inspection of pregnant women it is necessary to include definition of an index of the general weight. For local treatment of erosion-ulcer elements on MMOC at pregnant women with CRAS application of a preparation of local action FarGALS in the form of applications is shown. Complex treatment CRAS at pregnant women should include local use FarGALS with reception of probiotics under the scheme.

Degree of embed and economic effectivity: Results of research are introduced in practice of 3-clinic and faculty of therapeutic stomatology ТМА, faculties of stomatology TashATID (Tashkent Advanced Training Institute for Doctors), stomatologic polyclinics of Tashkent.

Field of application: Stomatology.